دورية
Inhibition of Neutrophil Function by Human Milk
| العنوان: | Inhibition of Neutrophil Function by Human Milk |
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| المؤلفون: | Grazioso, Carlos F., Buescher, E.Stephen |
| المصدر: | Cellular Immunology; March 1996, Vol. 168 Issue: 2 p125-132, 8p |
| مستخلص: | Human colostrum, the first product of lactation, has antioxidant properties and inhibits selected enzyme and bactericidal activities of human neutrophils. We examined the subsequent product of lactation, mature human milk, with respect to its antioxidant activities, its effects on neutrophil enzyme activities (myeloperoxidase, β-glucuronidase, and lysozyme), and its effects on neutrophil bactericidal and phagocytic activities. Mature human milk displayed antioxidant characteristics similar to those of human colostrum, reducing cytochrome c and consuming H2O2. Mature milk also displayed colostrum-like characteristics in depressing neutrophil myeloperoxidase and β-glucuronidase activities, but not in altering lysozyme activity. Neutrophil bactericidal activity againstStaphylococcus aureuswas depressed by both mature milk and colostrum, without dramatic effects on phagocytic activity. These data show that mature milk shares characteristics with human colostrum that may result in anti-inflammatory effects, but the magnitude of these effects is generally smaller. |
| قاعدة البيانات: | Supplemental Index |
Full Text Finder | تدمد: | 00088749 10902163 |
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| DOI: | 10.1006/cimm.1996.0058 |