دورية
Decreased α-Adrenergic Response in the Intestinal Microcirculation after “Two-Hit” Hemorrhage/Resuscitation and Bacteremia
| العنوان: | Decreased α-Adrenergic Response in the Intestinal Microcirculation after “Two-Hit” Hemorrhage/Resuscitation and Bacteremia |
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| المؤلفون: | Spain, David A., Kawabe, Touichi, Keelan, Patricia C., Wilson, Mark A., Harris, Patrick D., Garrison, R.Neal |
| المصدر: | Journal of Surgical Research; June 1999, Vol. 84 Issue: 2 p180-185, 6p |
| مستخلص: | Background.The two-hit theory of multiple organ dysfunction syndrome proposes that an initial insult primes the host for an altered response to subsequent stimuli. We have previously documented enhanced dilator tone in the small intestine after a two-hit insult; however, the effects on vasoconstrictor function are unknown. We postulated that prior hemorrhage and resuscitation followed by bacteremia would alter microvascular responsiveness to α-adrenergic stimulation. |
| قاعدة البيانات: | Supplemental Index |
Full Text Finder | تدمد: | 00224804 10958673 |
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| DOI: | 10.1006/jsre.1999.5638 |