دورية
Survey of GMP Bulk Reactions Run in a Research Facility between 1985 and 2002
| العنوان: | Survey of GMP Bulk Reactions Run in a Research Facility between 1985 and 2002 |
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| المؤلفون: | Dugger, R. W., Ragan, J. A., Ripin, D. H. B. |
| المصدر: | Organic Process Research & Development; May 2005, Vol. 9 Issue: 3 p253-258, 6p |
| مستخلص: | A review of reactions scaled in the GMP facilities at the Pfizer-Groton site was undertaken. Reactions were categorized into one of seven categories: carbon−carbon bond formation, carboxylic acid derivative interconversion, carbon−nitrogen bond formation, carbon−oxygen bond formation, red-ox, salt formation/resolution, and other. Reactions scaled from 1997 to 2002 were compared to chemistry scaled from 1985 to 1996 to look for changes in the nature of chemistry being scaled between the two time periods. Reactions were further subcategorized within those categories, and some interesting trends were noted. |
| قاعدة البيانات: | Supplemental Index |
Find this issue from the American Chemical Society | تدمد: | 10836160 1520586X |
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