دورية
Linkage Relationships between Keratin-Associated Protein (KRTAP) Genes and Growth Hormone in Sheep
| العنوان: | Linkage Relationships between Keratin-Associated Protein (KRTAP) Genes and Growth Hormone in Sheep |
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| المؤلفون: | Parsons, Y. M., Piper, L. R., Cooper, D. W. |
| المصدر: | Genomics; April 1994, Vol. 20 Issue: 3 p500-502, 3p |
| مستخلص: | The ovine hair keratin-associated protein (KRTAP) genes are grouped into several families. In this study, we analyzed linkage relationships between members of four KRTAP families and growth hormone and β-hemoglobin. Restriction fragment length polymorphisms and a microsatellite polymorphism were typed in 10 sire groups from a flock of Australian Merino sheep. Two linkages, both previously undetected in sheep or any other mammal, were found. They were between growth hormone (GH) and the high-sulfur keratin gene family KRTAP1 (previously called high-sulfur B2C) at θ = 0.10, Z = 3.01 and between two high-glycine-tyrosine class genes, KRTAP6 (previously high-glycine-tyrosine type II) and KRTAP8 (previously high-glycine-tyrosine type I-F), at θ - 0.15, Z = 5.0. The high level of conservation of the mammalian genome at these recombination values suggests that these linkages might be found in distantly related mammalian species. Copyright 1994, 1999 Academic Press |
| قاعدة البيانات: | Supplemental Index |
Full Text Finder | تدمد: | 08887543 10898646 |
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| DOI: | 10.1006/geno.1994.1209 |