التفاصيل البيبلوغرافية
| العنوان: |
Potential and limitations of magnetic resonance imaging for real-time monitoring of interstitial laser phototherapy |
| المؤلفون: |
Pignoli, E., Marchesini, R., Curti, L., Sichirollo, A.E., Tomatis, S., Musumeci, R. |
| المصدر: |
Academic Radiology; September 1995, Vol. 2 Issue: 9 p741-747, 7p |
| مستخلص: |
Rationale and Objectives.: Magnetic resonance (MR) imaging has been suggested as a method to monitor interstitial laser phototherapy (ILP) in deep tissues. Unfortunately, a reliable relation between temperature and MR parameters has not yet been demonstrated. In this study, we examined whether such a relation exists and whether MR imaging can measure absolute temperature or temperature changes. Methods.: We evaluated, in the range of 21^oC to 80^oC, the temperature dependence of the MR imaging signal and T1 in samples of liver, water, CuSO"4, and oil. Spin-echo and fast low-angle shot (FLASH) sequences were used. Results.: The MR imaging signal of liver, CuSO"4, and water continuously decreased when the temperature was increased from 21^oC to 80^oC. By contrast, the MR imaging signal of the oil increased with increasing temperature up to 40-50^oC and then decreased at higher temperatures. We observed a reliable linear relation only between T1 and temperature in a range of 30-60^oC for oil and CuSO"4. Conclusion.: MR imaging has the potential to measure thermal variations with an uncertainty of approximately +/-10^oC. However, the use of MR imaging to monitor the real-time thermal effect induced in biologic tissues during laser irradiation requires further investigation before it can be applied clinically. |
| قاعدة البيانات: |
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