دورية
Glucose and Glutamine Gavage Increase Portal Vein Nitric Oxide Metabolite Levels via Adenosine A2b Activation
| العنوان: | Glucose and Glutamine Gavage Increase Portal Vein Nitric Oxide Metabolite Levels via Adenosine A2b Activation |
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| المؤلفون: | Matheson, Paul J., Spain, David A., Harris, Patrick D., Garrison, R.Neal, Wilson, Mark A. |
| المصدر: | Journal of Surgical Research; June 1999, Vol. 84 Issue: 1 p57-63, 7p |
| مستخلص: | Introduction.Postprandial intestinal hyperemia is a complex vascular response during nutrient absorption. Many mediators have been studied including enteric reflexes, GI hormones, and absorption-stimulated metabolic mediators such as pH and adenosine. We have shown that nitric oxide (NO) mediates premucosal arteriolar dilation during glucose absorption and that glucose-induced portal vein NO metabolite production requires adenosine A2b receptor activation. We hypothesize that Na+-linked absorption ofl-glutamine orl-glycine might also stimulate NO release in the enteroportal circulation via adenosine A2b receptors. |
| قاعدة البيانات: | Supplemental Index |
Full Text Finder | تدمد: | 00224804 10958673 |
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| DOI: | 10.1006/jsre.1999.5604 |