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Relation of Interatrial Block to Cognitive Impairment in Patients >= 70 Years of Age (From the CAMBIAD Case-control Study)

التفاصيل البيبلوغرافية
العنوان: Relation of Interatrial Block to Cognitive Impairment in Patients >= 70 Years of Age (From the CAMBIAD Case-control Study)
المؤلفون: Herrera, C, Bruna, V, Abizanda, P, Diez-Villanueva, P, Formiga, F, Torres, R, Carreras, J, Ayala, R, Martin-Sanchez, FJ, Bayes-Genis, A, Elosua, R, Bayes-de-Luna, A, Martinez-Selles, M
المصدر: American Journal of Cardiology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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بيانات النشر: Elsevier Inc., 2020.
سنة النشر: 2020
الوصف: The association between atrial fibrillation, stroke, and interatrial block (IAB) (P-wave duration >= 120 ms) is well recognized, particularly in the case of advanced IAB. We aimed to assess the association of IAB with mild cognitive impairment. Advanced Characterization of Cognitive Impairment in Elderly with Interatrial Block was a case-control multicenter study, conducted in subjects aged >= 70 years in sinus rhythm without significant structural heart disease. Diagnosis of mild cognitive impairment was performed by an expert geriatrician, internist, or neurologist in the presence of changes in cognitive function (Mini Mental State Examination score 20 to 25) without established dementia. A total of 265 subjects were included. Mean age was 79.6 +/- 6.3 years and 174 (65.7%) were women; there were 143 cases with mild cognitive impairment and 122 controls with normal cognitive function. Compared with controls, cases had longer P-wave duration (116.2 +/- 13.8 ms vs 112.5 +/- 13.3 ms, p = 0.028), higher prevalence of IAB (73 [51.0%] vs 38 [31.1 %], p = 0.001), higher prevalence of advanced IAB (28 [19.6%] vs 10 [8.2 %], p = 0.002), and higher MVP ECG risk score (2.7 +/- 1.4 vs 2.2 +/- 1.3, p = 0.004). IAB was independently associated with mild cognitive impairment, both for partial (odds ratio 2.0, 95% CI: 1.1 to 3.9) and advanced IAB (odds ratio 2.8, 95% CI: 1.1 to 6.7). In conclusion, in subjects aged >= 70 years without significant structural heart disease, IAB is independently associated with mild cognitive impairment. This association is stronger in the case of advanced IAB. (C) 2020 Elsevier Inc. All rights reserved.
تدمد: 0002-9149
URL الوصول: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::5f824c63a4585a7d409128f0f253aebd
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4241
حقوق: OPEN
رقم الأكسشن: edsair.RECOLECTA.....5f824c63a4585a7d409128f0f253aebd
قاعدة البيانات: OpenAIRE
الوصف
تدمد:00029149