Prevalence of vitamin D deficiency and its predictors in the Portuguese population: a nationwide population-based study
| العنوان: | Prevalence of vitamin D deficiency and its predictors in the Portuguese population: a nationwide population-based study |
|---|---|
| المؤلفون: | Duarte, C, Carvalheiro, H, Rodrigues, A, Dias, S, Marques, A, Santiago, T, Canhão, H, Branco, J, Pereira da Silva, JA |
| المصدر: | Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP |
| بيانات النشر: | Springer, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Adult, Male, Adolescent, Vitamin D / analogs & derivatives, Vitamin D Deficiency / etiology, HCC REUM, Young Adult, Risk Factors, Surveys and Questionnaires, Prevalence, Humans, Portugal / epidemiology, Vitamin D / blood, Vitamin D, Exercise, Life Style, Aged, Vitamin D deficiency, Vitamin D insufficiency, Portugal, Age Factors, Vitamin D Deficiency / epidemiology, Middle Aged, 25-hydroxyvitamin D, Obesity / complications, Female, Seasons, Obesity / blood |
| الوصف: | Summary Vitamin D deficiency is prevalent worldwide, but its prevalence is unknown in adult Portuguese population. In Portugal, 66% of adults present Vitamin D insufficiency/deficiency. Winter, living in Azores, older age, and obesity were the most important risk factors. It highlights the need of strategies to prevent vitamin D deficiency in Portugal. Objective To estimate the prevalence and risk factors of vitamin D deficiency in the adult Portuguese population. Methods Adults (≥ 18 years old) from the EpiReumaPt Study (2011–2013) were included. Standardized questionnaires on sociodemographic and lifestyle features were obtained. Serum 25-hydroxyvitamin D [25(OH)D] concentrations were evaluated using ADVIA Centaur VitD competitive immunoassay (Siemens Healthineers) in 2015–2017 as 25 (OH)D Level 0: ≤ 10 ng/mL; Level 1: 11–19 ng/mL; Level 2: 20–29 ng/mL, and Level 3: ≥ 30 ng/mL. Weighted multinomial regression analysis was conducted to evaluate the association between socio-demographic and lifestyle variables and vitamin D status. Results Based on weighted analysis, the estimated prevalence of levels of 25(OH)D ≤ 10, < 20, and < 30 ng/mL was 21.2, 66.6, and 96.4%, respectively. The strongest independent predictors of serum 25 (OH)D ≤ 10 ng/mL were living in the Azores archipelagos (OR 9.39; 95%CI 1.27–69.6) and having the blood sample collection in winter (OR 18.53; 95%CI 7.83–43.87) or spring (11.55; 95%CI 5.18–25.74). Other significant predictors included older age (OR 5.65, 95%CI 2.08–15.35), obesity (OR 2.61; 95%CI 1.35–5.08), current smoking (OR 2.33; 95%CI 1.23–4.43), and female gender (OR 1.9, 95%CI 1.1–3.28). Conversely, physical exercise (OR 0.48, 95%CI 0.28–0.81) and occasional alcohol intake (OR 0.48, 95%CI 0.29–0.81) were associated with a lower risk of 25(OH)D ≤ 10 ng/mL. Conclusion Vitamin D deficiency/insufficiency [25(OH)D < 20 ng/ml] is highly prevalent in Portugal, affecting > 60% of all Portuguese adults, with strong geographical and seasonal variation. This study highlights the need to critically assess the relevance of vitamin D deficiency as a public health problem and the urgent need for a wide and scientifically robust debate about the most appropriate interventions at the individual and societal levels. info:eu-repo/semantics/publishedVersion |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0765bac5e0274b04d651aca60982cc37 https://hdl.handle.net/10400.8/6653 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.dedup.wf.001..0765bac5e0274b04d651aca60982cc37 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |