Deep Brain Stimulation for Parkinson’s Disease: Anatomical Location of Effective Contacts in the Sub Thalamic Area
| العنوان: | Deep Brain Stimulation for Parkinson’s Disease: Anatomical Location of Effective Contacts in the Sub Thalamic Area |
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| المؤلفون: | François Caire, Derost, Philippe P., Jérôme Coste, Franck Durif, Emmanuelle Frenoux, Jean-Jacques Lemaire |
| المساهمون: | Service de Neurochirurgie [CHU Limoges], CHU Limoges, Service de Neurochirurgie [CHU Clermont-Ferrand], CHU Gabriel Montpied [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand, Equipe de Recherche en Signal et Imagerie Medicale (ERIM-ERI 14), Université d'Auvergne - Clermont-Ferrand I (UdA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Neurologie [CHU Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand-CHU Estaing [Clermont-Ferrand], CHU Clermont-Ferrand, Neuro-Psycho Pharmacologie des Systèmes Dopimanégiques sous-corticaux (NPsy-Sydo), CHU Clermont-Ferrand-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), European Society for Stereotactic and Functional Neurosurgery (ESSFN), Service de Neurochirurgie [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Gabriel Montpied [Clermont-Ferrand], CHU Estaing [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand-CHU Gabriel Montpied [Clermont-Ferrand], Société Française de NeuroChirurgie (SFNC) et Deutschen Gesellschaft für NeuroChirurgie (DGNC), Coste, Jérôme |
| المصدر: | Acta Neurochirurgica XVIth Congress of the European Society for Stereotactic and Functional Neurosurgery (ESSFN) XVIth Congress of the European Society for Stereotactic and Functional Neurosurgery (ESSFN), European Society for Stereotactic and Functional Neurosurgery (ESSFN), Jun 2004, Vienne, Austria. pp.869-870, ⟨10.1007/s00701-004-0301-9⟩ Journées de la Société Française de NeuroChirurgie, et de la Deutschen Gesellschaft für NeuroChirurgie Journées de la Société Française de NeuroChirurgie, et de la Deutschen Gesellschaft für NeuroChirurgie, Société Française de NeuroChirurgie (SFNC) et Deutschen Gesellschaft für NeuroChirurgie (DGNC), May 2005, Strasbourg, France. pp.02-01 HAL |
| بيانات النشر: | HAL CCSD, 2004. |
| سنة النشر: | 2004 |
| مصطلحات موضوعية: | Parkinson's Disease, [SDV.MHEP.CHI] Life Sciences [q-bio]/Human health and pathology/Surgery, Contacts, Location, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, [SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, [INFO.INFO-IM] Computer Science [cs]/Medical Imaging, [INFO.INFO-IM]Computer Science [cs]/Medical Imaging, [SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery |
| الوصف: | International audience; The location of effective contacts during deep brain stimulation (DBS) is still debated in particular in the sub thalamic area.Objectives : To localise on 1.5 T MRI, the effective contacts in patients successfully treated for Parkinson’s disease by bilateral DBS of the sub thalamic nucleus (STN).Material and methods : Ten patients with excellent clinical outcome were analysed. The surgical procedure was based on direct targeting of the nucleus (anatomic targeting without reference to internal landmarks). The effective contacts were determined during the first 6 months following the implantation, i.e. those given the best efficacy on the clinical symptoms (mean improvement rate 82.5%, range 75.8–94.1%). The contact locations were retrospectively projected on the stereotactic 1.5 T MRI (3 sets, orthogonal plans), i.e. with a stereotactic frame. For each patient, we have distinguished the right and the left hemisphere. The location of the effective contacts was directly studied by visual comparison, between the 1.5 T images and an in-house 4.7 T MRI anatomic reference. The membership for a given structure was determined using the results for each orthogonal, independent plan.Results : The effective contact were located within the STN in 4 cases, at the interface of the STN and the zona incerta (ZI) and/or the Forel’s field (FF) in 12 cases, at the interface between ZI and FF in 3 cases, at the interface between the STN and the substantia nigra in one case.Discussion : The dorsolateral part of the STN is usually considered as the target for DBS in Parkinson’s disease. We discuss the role of adjacent structures, especially ZI and FF, in the clinical benefit. A largest study, including 56 patients is already in progress to assess and to refine these results. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::13275273652975249e23cbc8eda68926 https://hal.science/hal-01875309/file/Caire_ESSFN_2004.pdf |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.dedup.wf.001..13275273652975249e23cbc8eda68926 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |