| الوصف: |
There is increasing evidence for a sudden and unprecedented rise in the incidence of multiple sclerosis (MS) in Westernized countries over the past decades, emphasizing the role of environmental factors. Among many candidates, rapid changes in dietary habits seem to play a role in the pathogenesis of MS. Here, we summarize and discuss the available evidence for the role of dietary nutrients, such as table salt, fatty acids, and flavonoids, in the development and pathogenesis of MS. We also discuss new and emerging risk factors accompanying Western lifestyle, such as shift work, sleep, and circadian disruption. M.K. was supported by the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (640116), by an SALK grant from the government of Flanders, Belgium, and by an Odysseus grant from the Research Foundation Flanders, Belgium (FWO). J.H. and J.B. are supported by the FWO and the Charcot Foundation Belgium. R.A.L. holds an endowed professorship supported by Novartis Pharma. |
