Fluoxetine accumulation and metabolism as exposurebiomarker to better understand biological effects in gastropods
| العنوان: | Fluoxetine accumulation and metabolism as exposurebiomarker to better understand biological effects in gastropods |
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| المؤلفون: | Gust, M., Cren Olivé, C., Bulete, A., Buronfosse, T., Garric, J. |
| المساهمون: | Milieux aquatiques, écologie et pollutions (UR MALY), Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA), Service Central d'Analyse, Centre National de la Recherche Scientifique (CNRS), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS), Milieux aquatiques, écologie et pollutions ( UR MALY ), Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture ( IRSTEA ), Centre National de la Recherche Scientifique ( CNRS ), VetAgro Sup ( VAS ), Service Central d'Analyse (SCA), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC) |
| المصدر: | Journal of Xenobiotics Journal of Xenobiotics, Page Press publications, 2013, 3 (1S), pp.8-10 Journal of Xenobiotics, 2013, 3 (1S), pp.8-10 |
| بيانات النشر: | HAL CCSD, 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | [ SDE ] Environmental Sciences, TOXICITE, [SDE]Environmental Sciences, BIOMARQUEUR, FLUOXETINE, GASTEROSTEIDAE |
| الوصف: | International audience; Fluoxetine is a widely used antidepressant frequently found in wastewater treatment plant effluent and in aquatic ecosystems at concentrations below μg/L. Numerous studies have explored the sensitivity of invertebrates to waterborne fluoxetine showing marked differences of sensitivity. In a previous study, the New-Zealand mudsnail, Potamopyrgus antipodarum, and the European valve snail, Valvata piscinalis, were exposed to waterborne fluoxetine (3.7-100 μg/L) during 42 days. While effects were observed on the mudsnail reproduction and F1, the valve snail was not affected. Several assumptions were proposed to explain these results including dissimilar metabolic capacities or bioavailability of fluoxetine for the snails. The aim of this study was to asses if differential sensitivity of gastropods snails to fluoxetine could be explained by its bioaccumulation and metabolism into norfluoxetine. |
| اللغة: | English |
| تدمد: | 2039-4713 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::42070a5f319a70750f94ce46a0908c0b https://hal.archives-ouvertes.fr/hal-01117940/document |
| رقم الأكسشن: | edsair.dedup.wf.001..42070a5f319a70750f94ce46a0908c0b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20394713 |
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