Actinic cheilitis prevalence and risk factors: A cross-sectional, multi-centre study in a population aged 45 years and over in Galicia-Spain
| العنوان: | Actinic cheilitis prevalence and risk factors: A cross-sectional, multi-centre study in a population aged 45 years and over in Galicia-Spain |
|---|---|
| المؤلفون: | Rodríguez Blanco, María Isabel |
| المساهمون: | Pereiro Ferreirós, Manuel, Flórez Menéndez, Ángeles, Universidade de Santiago de Compostela. Escola de Doutoramento Internacional (EDIUS), Universidade de Santiago de Compostela. Programa de Doutoramento en Investigación Clínica en Medicina |
| المصدر: | Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela Universidad de Santiago de Compostela (USC) Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela instname |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | stomatognathic diseases, Investigación::32 Ciencias médicas::3202 Epidemologia [Materias], Investigación::32 Ciencias médicas::3201 Ciencias clínicas::320106 Dermatología [Materias], prevalencia, Investigación::32 Ciencias médicas::3207 Patología::320703 Carcinogénesis [Materias], queratosis actínicas, Actinic cheilitis (AC), cáncer cutáneo, epidemiología |
| الوصف: | Actinic cheilitis (AC) is an abnormal condition of the lower lip and is considered a superficial form of squamous cell carcinoma (SCC). Chronic sun exposure is the main risk factor for the development of AC. Evidence shows that the clinical appearance of AC correlates poorly with the degree of cellular dysplasia; this means that even when accuracy of diagnosis can be increased with new imaging techniques (such as dermoscopy and confocal microscopy), it is necessary to biopsy suspicious lesions to rule out invasive SCC, the most important differential diagnosis of AC. The actual rate of progression of AC to invasive SCC has not been established, but because SCC on the lip is considered a high-risk location, analysing the risk factors of AC is imperative for preventing invasive SCC. As stated above, even though solar radiation is the main risk factor for AC, there is little evidence regarding specific lip photoprotection. The prevalence of AC in Europe is unknown to date. Some epidemiological studies on AC have been conducted in specific populations primarily in Brazil, South America, but comparing their results is difficult owing to their heterogeneous design and the absence of a uniform definition of AC. Specific lip photoprotection has been poorly analysed in the past. The clinical presentation of AC has been described in various studies, but the possible association between its clinical manifestations and risk factors has not been reported to date. Further, actinic damage markers in AC patients have not been analysed. To address this knowledge gap, we designed a cross-sectional multi-centre study in a Western country with a predominantly Caucasian population to assess the prevalence of AC, analyse its risk factors and clinical manifestations, and investigate the use of specific lip photoprotection. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6039034d4b69efba7f95161afc9801d4 https://hdl.handle.net/10347/26058 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.dedup.wf.001..6039034d4b69efba7f95161afc9801d4 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |