The impact of gravity vs suction-driven therapeutic thoracentesis on pressure-related complications: the GRAVITAS multicenter randomized controlled trial
| العنوان: | The impact of gravity vs suction-driven therapeutic thoracentesis on pressure-related complications: the GRAVITAS multicenter randomized controlled trial |
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| المؤلفون: | Lentz, R, Shojaee, S, Grosu, H, Rickman, O, Roller, L, Pannu, J, Depew, Z, Debiane, L, Cicenia, J, Akulian, J, Walston, C, Sanchez, T, Davidson, K, Jagan, N, Ahmad, S, Gilbert, C, Huggins, J, Chen, H, Light, R, Yarmus, L, Feller-Kopman, D, Lee, H, Rahman, N, Maldonado, F, Group, Interventional Pulmonary Outcomes |
| المصدر: | Chest. |
| سنة النشر: | 2019 |
| الوصف: | BACKGROUND: Thoracentesis can be accomplished by active aspiration or drainage with gravity. We investigated whether gravity drainage could protect against negative-pressure related complications, such as chest discomfort, re-expansion pulmonary edema or pneumothorax, compared to active aspiration. METHODS: This prospective, multicenter single blinded randomized controlled trial allocated patients with large free-flowing effusions estimated ≥ 500 mL 1:1 to active aspiration or gravity drainage. Patients rated chest discomfort on 100 mm visual analog scales before, during, and after drainage. Thoracentesis was halted at complete evacuation or for persistent chest discomfort, intractable cough, or other complication. The primary outcome was overall procedural chest discomfort scored five minutes post-procedure. Secondary outcomes included measures of discomfort and breathlessness through 48 hours post-procedure. RESULTS: One hundred forty-two patients were randomized with 140 in the final analysis. Groups did not differ for the primary outcome (mean VAS score difference 5.3 mm, 95% CI -2.4 to 13.0, p = 0.17). Secondary outcomes of discomfort and dyspnea did not differ between groups. Comparable volumes were drained in both groups but procedure duration was significantly longer in the gravity arm (mean difference 7.4 minutes, 95% CI 10.2 to 4.6, p |
| اللغة: | English |
| تدمد: | 1931-3543 0012-3692 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a9b5627714a450786407011f44426e11 http://ora.ox.ac.uk/objects/uuid: |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.dedup.wf.001..a9b5627714a450786407011f44426e11 |
| قاعدة البيانات: | OpenAIRE |
Full Text via ClinicalKey | تدمد: | 19313543 00123692 |
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