PREVALENCE AND QUALITY OF LIFE OF PEMPHIGUS PATIENTS AT SANGLAH GENERAL HOSPITAL BALI-INDONESIA
| العنوان: | PREVALENCE AND QUALITY OF LIFE OF PEMPHIGUS PATIENTS AT SANGLAH GENERAL HOSPITAL BALI-INDONESIA |
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| المؤلفون: | M Wardhana, L Rusyati |
| المصدر: | Bali Medical Journal, Vol 2, Iss 1, Pp 42-45 (2013) |
| بيانات النشر: | DiscoverSys, 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | lcsh:R5-920, integumentary system, quality of life, retrospective study, lcsh:R, pemphigus, lcsh:Medicine, skin and connective tissue diseases, lcsh:Medicine (General) |
| الوصف: | Objectives: Pemphigus vulgaris (PV) is an autoimmune-blistering disease of the skin and mucous membranes caused by auto-antibodies against desmoglein-3 (Dsg-3) on the keratinocyte cell surface of squamous stratified epithelia. Pemphigus is a life-threatening autoimmune bullous disease resulting in the widespread denudation of skin and mucous membrane and severe impact of quality of life. Thepurpose of this study was to evaluate retrospectively the prevalence of pemphigus and to elucidate the clinical variants, clinical course, prognosis and quality of life (QOL) of pemphigus patients after discharge from hospitalized.Method: Observational non analytical retrospective study was conducted by observation of the medical records of all the newly registered patients with pemphigus at SanglahGeneral Hospital in Bali-Indonesia during the period of January 1995 and December 2002, and analyzed with regard to personal statistic, history of the diseases including onset, site of affected, symptoms, clinical diagnosis, severity, associated illness, therapy, and quality of life based on theFinlay’s methods.Results: During the 8-year periods studies, 33 pemphigus patients were admitted, represented 5.8 % of all patients admitted in our in-patient ward during the periods. Our patients consist of female 20 patients (60.6 %) and male 13 patients (39.4 %). The most common of clinicaltype was pemphigus vulgaris 26 patients (78.78 %), followed by pemphigus foleaceous and pemphigus vegetans. Six patients (18.18 %) of 16 severe patients with severe condition at the clinical course of the diseases was death during the course of hospitalized. A number of 2 patients, in thisstudy were observed with severe impact of quality of life.Conclusion: Our finding showed that pemphigus vulgaris is common type of our cases has a relatively high prevalence our hospital (5.8 %), and relatively high death rate (18.18 %). In our study, systemic corticosteroid was still applied untilpresent for life saving drug for Pemphigus. |
| اللغة: | English |
| تدمد: | 2302-2914 2089-1180 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doajarticles::0911f117937a354ab25d5d78de3c410a https://balimedicaljournal.org/index.php/bmj/article/view/38 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doajarticles..0911f117937a354ab25d5d78de3c410a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23022914 20891180 |
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