Objective: To summarize and analyze the clinical treatment experience of Vibrio vulnificus sepsis and improve the success rate of treatment. Methods: The clinical data of a patient with vibrio vulnificus sepsis admitted to the Department of Critical Care Medicine, the First Affiliated Hospital of Hainan Medical College in October 2019 were analyzed. Summarize the experience of treatment and compare with other literatures to analyze the most reasonable clinical treatment of vibrio vulnificus sepsis. Results: The patient was acutely ill, the disease progressed rapidly, fever, soft tissue swelling and pain, necrosis, ulceration and pus, systemic multiple organ failure, family members finally gave up treatment, microbiology culture prompted: Vibrio parahaemolyticus. Conclusions: Early intervention, blood purification, debridement, removal of infection sources and inflammatory mediators can improve the survival rate of patients with Vibrio vulnificus infection. Due to the high mortality rate, clinicians should pay attention to it.
