The paper presents a designed and manufactured, semi-industrial microwave reactor for thermal utilization of asbestos-bearing wastes. Presented are also semi-industrial tests of utilizing such wastes. It was found that microwave heating can be applied for utilizing asbestos with use of suitable wetting agents. The wetting agents should ensure continuous heating process above 600 °C, as well as uniform heat distribution in the whole volume of the utilized material. Analysis of the neutralization process indicates a possibility of presenting specific, efficient and effective process parameters of utilizing some asbestos-bearing industrial wastes.