Effects of cadmium and copper on sialic acid levels in blood and brain tissues of Cyprinus carpio L
| العنوان: | Effects of cadmium and copper on sialic acid levels in blood and brain tissues of Cyprinus carpio L |
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| المؤلفون: | Utku Güner, Elvan Bakar |
| المصدر: | Journal of Coastal Life Medicine, Vol 2, Iss 9, Pp 673-678 (2014) |
| بيانات النشر: | Journal of Coastal Life Medicine Editorial Office, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | lcsh:R5-920, Blood, Cyprinus carpio, lcsh:Biology (General), Carp, Brain, Metal accumulation, lcsh:Medicine (General), lcsh:QH301-705.5, Copper, Sialic acid, Cadmium |
| الوصف: | Objective: To investigate the effects of cadmium (Cd) and copper (Cu) on sialic acid levels of brain and blood tissues of Cyprinus carpio. Methods: Adult carps were exposed to 0.1, 0.5 mg/L Cu, 0.1, 0.5 and 1.0 mg/L Cd and 0.1 mg/ L Cu+0.1 mg/L Cd under static experiment conditions for 1 week. At the end of exposure period, heavy metal accumulations and sialic acid levels in blood and brain tissues of the test animals were analyzed. Results: Cu and Cd accumulated in tissues in a dramatically increasing dose-dependent manner. Sialic acids level of the fish exposed to 0.1, 0.5 and 1.0 mg/L Cu and Cd and control grups for 1 week were 0.834, 1.427, 0.672, 0.934, 2.968, 4.714 mg/mL respectively. The results also showed that Cu has an antagonistic effect on tissue sialic acid level. Conclusions: We propose that Cd and Cu make a complex with sialic acids of membranes in the tissues researched. This complex between metal ions and sialic acid migth account for the cellular toxicity based on Cu and Cd. |
| اللغة: | English |
| تدمد: | 2309-6152 2309-5288 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doajarticles::f2b5630c91e18bab8a903f18b6a58d0e http://www.jclmm.com/qk/20149/1.pdf |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doajarticles..f2b5630c91e18bab8a903f18b6a58d0e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23096152 23095288 |
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