Noncanonical and Strongly Disallowed Conformations of the Backbone in Polypeptide Chains of Globular Proteins
| العنوان: | Noncanonical and Strongly Disallowed Conformations of the Backbone in Polypeptide Chains of Globular Proteins |
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| المؤلفون: | A. V. Batyanovskii, L. A. Uroshlev, I. Yu. Torshin, Natalia G. Esipova, Vladimir G. Tumanyan |
| المصدر: | Biophysics. 63:149-153 |
| بيانات النشر: | Pleiades Publishing Ltd, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | 0301 basic medicine, chemistry.chemical_classification, Physics, 03 medical and health sciences, Crystallography, 030104 developmental biology, 030102 biochemistry & molecular biology, chemistry, Globular protein, Biophysics, Classification methods, Polypeptide chain, Ramachandran plot |
| الوصف: | An analog of the Ramachandran map was drawn, a new representation proposed, and thorough analysis performed using modern recognition and classification methods. Very large maps with a density of more than 50 million dots were created based on the data sets derived from the latest releases of globular protein- structure data banks. A, B, B', C, and D regions that correspond to strongly disallowed conformations were defined and found to occupy 25% of the plot area. A region of noncanonical conformations was determined by subtracting strongly disallowed and permitted conformation regions from the total plot area. Arguments are provided to support the new classification of backbone conformations of the protein polypeptide chain. |
| تدمد: | 1555-6654 0006-3509 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::0132b3b574d7840cb64abc6f07758307 https://doi.org/10.1134/s0006350918020240 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........0132b3b574d7840cb64abc6f07758307 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 15556654 00063509 |
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