The arbitrary utilization of pesticides has caused several perils for both environment and human health. Occupational exposure to pesticides occurs mostly in the agricultural field where workers are more prone to pesticides poisoning and toxicity. Prior studies have proved that pesticides metabolism results in emission of free radicals and reactive oxygen species (ROS) that provoke cellular oxidative stress. Defensive systems of enzymatic and nonenzymatic antioxidants scavengers play a vital role in the elimination of released free radicals and ROS. If the body could not overcome the increasing rate of oxidative stress, the risk of oxidative cellular damage at the molecular and genetic levels would elevate. Impaired antioxidants defense system is considered one of the main triggered mechanisms for induction of numerous pesticides linked diseases. Nowadays, great attention has been given to the health impact of antioxidants not only to manage the cellular oxidative damages but also to inhibit pesticides related cyotoxicity, genotoxicity, and carcinogenicity.
