One-pot access to tetrahydrobenzo[c]carbazoles from simple ketones by using O2 as an oxidant
| العنوان: | One-pot access to tetrahydrobenzo[c]carbazoles from simple ketones by using O2 as an oxidant |
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| المؤلفون: | Modhu Sudan Maji, Shuvendu Saha |
| المصدر: | Organic & Biomolecular Chemistry. 18:1765-1768 |
| بيانات النشر: | Royal Society of Chemistry (RSC), 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | chemistry.chemical_compound, Chemistry, Carbazole, Organic Chemistry, Molecular oxygen, Physical and Theoretical Chemistry, Brønsted–Lowry acid–base theory, Protecting group, Biochemistry, Combinatorial chemistry, Catalysis |
| الوصف: | An effective and operationally simple one-pot Bronsted acid catalyzed cascade method is demonstrated for the synthesis of diversely functionalized carbazole frameworks starting from protecting group free 2-alkenyl indoles. The employment of easily available unactivated ketones as annulating partners, mostly unexplored for the synthesis of carbazoles, is the major highlight of this protocol. This protocol is step- and atom-economical, uses molecular oxygen as the green oxidant, and gives water as the only by-product and is amenable to different functional groups. Moreover, gram-scale synthesis and downstream modification of the obtained products demonstrate the synthetic applicability of this protocol. |
| تدمد: | 1477-0539 1477-0520 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::0227f1cf1ad7b4a6c23219908b1981e5 https://doi.org/10.1039/c9ob02751c |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........0227f1cf1ad7b4a6c23219908b1981e5 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14770539 14770520 |
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