Glasser’s disease is an infectious and acute disease seen in pig after weaning, which is characterized by fibrinous polysterositis, arthritis and meningoencephalitis. A case of 3 month old piglet breed “Chwanche” (local) was presented to Veterinary Teaching Hospital (VTH), Institute of Agriculture and Animal Science (IAAS), Paklihawa Campus which chief complain of constipation since three day. Piglet was admitted on VTH and physical and clinical examination was done and heart rate, respiratory rate and temperature were 130/min, 60/min and 106°F respectively. Auscultations abdomen revealed burble sound. First phase treatment was done and further examination was started with hematology. PCV and WBC count were 38% and (28×103/µl) but after five hours the pig was died and postmortem examination was done. Necropsy findings reveals severe polyserositis, fibrinous covering around the lungs and heart, Swollen liver with fibrinous deposition and congested intestinal epithelium. Sever polyserositis indicates that this case is a glasser`s disease.
