The Strychnos innocua (monkey orange) fruits were randomly collected from various locations in Zuru town of Kebbi State, Nigeria. The seeds of mature fruits were separated manually from the pulp and analysed for proximate, minerals, anti-nutritional compositions and physico-chemical analysis. The results showed that, the seed on dry weight basis (DW) contained crude protein (9.36±0.29%), crude lipid (25.0±0.82%), ash (6.0± 0.14%), available carbohydrates (56.31± 0.50%) and calorific value (487.67± 67.55 kcal/100g). The mineral elements (mg/100g DW) analysed showed that, the seed is rich in potassium (383.33±12.47), sodium (203.33±20.55), magnesium (23.67±1.25), iron (5.97 ±0.05), zinc (21.47±0.05), and manganese (3.67±0.05). Results of anti-nutritional analysis in the samples indicates high content of total oxalate (26.25±5.30mg/100gDW) and phytic acid (858.95±13.14mg/100gDW) respectively. With corresponding low concentration of cyanogenic glycosides, nitrate and saponins. Prediction of minerals bioavailability indicated that calcium and iron are not bioavailable due to oxalate and phytate content of the fruit. The oil had Saponification, Iodine, acid and Peroxide value of 151.20±0.16mgKOH/g oil, 14.53±0.06g/100g, 14.55±0.26mgKOH/g oil and 8.06±0.49meq/kg oil respectively.
