Disruption of bacterial biofilms using recombinant dispersin B
| العنوان: | Disruption of bacterial biofilms using recombinant dispersin B |
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| المؤلفون: | Tatyana N. Bolshakova, Z. M. Galushkina, Anna S. Karyagina, I. A. Shaginian, A. M. Lyashchuk, A. V. Grishin, O. Yu. Dobrynina, N V Lavrova, A.M. Umyarov, I. S. Boksha, L. R. Avetisian, M. Yu. Chernukha, Vladimir G. Lunin |
| المصدر: | Microbiology. 84:498-501 |
| بيانات النشر: | Pleiades Publishing Ltd, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | biology, Burkholderia cenocepacia, Chemistry, Aggregatibacter actinomycetemcomitans, Biofilm, Achromobacter xylosoxidans, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, medicine.disease_cause, Applied Microbiology and Biotechnology, Microbiology, law.invention, law, Staphylococcus epidermidis, Recombinant DNA, medicine, Dispersin B, Escherichia coli |
| الوصف: | A synthetic gene encoding dispersin B of Aggregatibacter actinomycetemcomitans was cloned and expressed in Escherichia coli cells. Procedure for purification of recombinant dispersin B was developed, and its in vitro activity was determined. The enzyme was used in experiments on disruption of the biofilms formed by various microorganisms. It exhibited high activity against Staphylococcus epidermidis biofilms. The biofilms formed by Burkholderia cenocepacia and Achromobacter xylosoxidans were more resistant to the recombinant enzyme. |
| تدمد: | 1608-3237 0026-2617 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::063fdff99ad7059b07efe8903924d66e https://doi.org/10.1134/s0026261715040062 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........063fdff99ad7059b07efe8903924d66e |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 16083237 00262617 |
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