Climate change, violence against women (VAW), and modern slavery are significant human rights crises to which women are disproportionately vulnerable. Our research examined the complex relationship between indicators of climate change, VAW, and the estimated prevalence of modern slavery across 180 countries. Regression analysis revealed significant results suggesting that countries where climate change and VAW are prevalent may support conditions that exacerbate vulnerability to exploitation. Results are placed within a gender framework, highlighting ecofeminism theory for an examination of patriarchal and capitalistic systems and their relationship to the oppression of women, the degradation of the environment, and modern slavery.