The Bank of Biological Samples by Seversk Biophysical Research Center
| العنوان: | The Bank of Biological Samples by Seversk Biophysical Research Center |
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| المؤلفون: | L. Takhauova, T. Takhauova, M. Khalyuzova, E. Bronikovskaya, O. Tsymbal, Karpov Ab, D. Isubakova, I. V. Mil’to, Nicolay V. Litviakov |
| المصدر: | Medical Radiology and radiation safety. 65:21-26 |
| بيانات النشر: | Burnasyan Federal Medical Biophysical Center Of Federal Medical Biological Agency, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 03 medical and health sciences, 0302 clinical medicine, Nuclear Energy and Engineering, business.industry, Environmental resource management, 0402 animal and dairy science, Environmental science, 030216 legal & forensic medicine, 04 agricultural and veterinary sciences, business, 040201 dairy & animal science, Research center |
| الوصف: | Purpose: Description of the collection, structure and development dynamics during the period from 2015 to 2019 of the biological material bank of the Seversk Biophysical Research Center, as well as research works carried out using biological material from its collection. Material and methods: The collection of bank of biological material includes the following types of biological material: venous blood, genomic DNA of white blood cells, cytogenetic suspensions of blood lymphocytes, surgical, biopsy and autopsy material. Biological material was obtained from people exposed to chronic radiation exposure: employees of the nuclear industry and the population permanently residing in the territory located in the area of the nuclear industry. Results: At present, the collection of the biological material bank contains more than 21,000 samples of biological material obtained from more than 8,000 donors. The collection of bank of biological material is represented by 4 main blocks: biological material of conditionally healthy employees of company of the nuclear industry (Siberian Chemical Combine); biological material of conditionally healthy people permanently residing in the territory located in the area of the nuclear industry enterprise (Seversk); biological material of patients (workers of the Siberian Chemical Combine and residents of Seversk) with malignant neoplasms and biological material of patients (workers of the Siberian Chemical Combine and residents of Seversk) with acute myocardial infarction. In the collection of bank of biological material, the proportion of samples of biological material of relatively healthy workers of the Siberian Chemical Combine is 33 %, residents of Seversk — 40.8 %, patients with malignant neoplasms — 22.2 %, patients with acute myocardial infarction — 4 %. Conclusion: Biological material bank Seversk Biophysical Research Center is unique collection of biological material samples of healthy people and patients with socially significant diseases. A feature of the biological material of the biological material bank is that it is obtained from people who have been exposed to chronic low-intensity radiation exposure and can be used to evaluate its radiogenic effects. |
| تدمد: | 2618-9615 1024-6177 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::0e67ae6934f21d48a590824e27398700 https://doi.org/10.12737/1024-6177-2020-65-2-21-26 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........0e67ae6934f21d48a590824e27398700 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 26189615 10246177 |
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