Fusariosis can cause disseminated infection among individuals with severely impaired immunity, representing the second leading cause of invasive fungal infection with poor prognosis and often leading to death in those individuals. The authors describe five cases of immune compromised/ neutropenic patients hospitalized in the Clementino Fraga Filho University hospital hematology ward with this fungal infection. It is of utmost importance for Dermatologists and Oncologists to know about this association.