Mortality Outcomes With Intensive Blood Pressure Targets in Chronic Kidney Disease Patients
| العنوان: | Mortality Outcomes With Intensive Blood Pressure Targets in Chronic Kidney Disease Patients |
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| المؤلفون: | Rahul Aggarwal, Benjamin Petrie, Wasif Bala, Nicholas Chiu |
| المصدر: | Hypertension. 73:1275-1282 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | education.field_of_study, medicine.medical_specialty, business.industry, Population, 030204 cardiovascular system & hematology, medicine.disease, 03 medical and health sciences, 0302 clinical medicine, Blood pressure, Internal medicine, Internal Medicine, medicine, 030212 general & internal medicine, education, business, Kidney disease |
| الوصف: | Hypertension is highly prevalent and morbid in the chronic kidney disease population, and blood pressure (BP) targets for this population are unclear. We aimed to compare all-cause mortality outcomes with intensively targeting systolic BP to 2 along with those undergoing intensive glycemic control. The primary outcome was all-cause mortality. Average achieved BP was 125.0 mm Hg in the intensive group and 136.9 mm Hg in the standard group. In the primary analysis, the all-cause mortality rate trended towards improved outcomes with intensive treatment but was not statistically significant (hazard ratio: 0.87 [0.69–1.08]; P =0.21). One hundred seventy-three of 2474 patients (1.95% per year) in the standard group and 153 of 2509 patients (1.71% per year) in the intensive group died. After excluding patients with higher glomerular filtration rate values and those undergoing intensive glycemic control, there was a statistically significant decrease in all-cause mortality rate (hazard ratio: 0.79 [0.63–1.00]; P =0.048). An intensive BP target of |
| تدمد: | 1524-4563 0194-911X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::11918a9bd3623e7036ee4e74bc2f2e83 https://doi.org/10.1161/hypertensionaha.119.12697 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........11918a9bd3623e7036ee4e74bc2f2e83 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15244563 0194911X |
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