Patients with neurodegenerative diseases currently have few treatment options. However, neurotransplantation represents one potential treatment avenue. Animal studies using lesion-induced models of neurodegenerative disorders such as Parkinson’s disease, Huntington’s disease and Alzheimer’s disease have shown that transplantation of appropriate fetal tissue can improve motor and cognitive deficits. Clinical trials of transplantation for Parkinson’s disease and, recently, Huntington’s disease have demonstrated limited success in controlling symptoms, with some patients exhibiting greater improvement than others.
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