Synthesis of 6-Cycloalkyl-2(3H)-benzoxazolones and Benzoxathiazolones via 6-Tri-N-butyltin Intermediates
| العنوان: | Synthesis of 6-Cycloalkyl-2(3H)-benzoxazolones and Benzoxathiazolones via 6-Tri-N-butyltin Intermediates |
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| المؤلفون: | Nicolas Lebegue, Jacques Poupaert, Pascal Carato, Ziaeddine Moussavi, S. Yous, Pascal Berthelot |
| المصدر: | ChemInform. 35 |
| بيانات النشر: | Wiley, 2004. |
| سنة النشر: | 2004 |
| مصطلحات موضوعية: | Acylation, chemistry.chemical_compound, Tri-n-butyltin, chemistry, Reagent, Tributyltin, chemistry.chemical_element, Substrate (chemistry), Molecule, General Medicine, Sulfur, Combinatorial chemistry, Lewis acid catalysis |
| الوصف: | Friedel-Crafts acylation of highly activated aromatic nuclei is rendered difficult by the fact that extensive complexation of the substrate by the Lewis acid catalyst inevitably takes place, which deactivates more or less completely such reagents. 2(3H)-benzoxazolones and their sulfur bioisosters were chosen as model molecules in an effort to search for an efficient alternative method to the Friedel-Crafts reaction. 6-Cyclo-alkylcarbonyl-3-methyl-2(3H)-benzoxazolones and benzothiazolones which cannot be synthesized by classical Friedel-Crafts approach are expeditiously obtained via tributyltin intermediates to afford the desired compounds in good yields. |
| تدمد: | 1522-2667 0931-7597 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::167547c818d6516454e0884b574300d3 https://doi.org/10.1002/chin.200449117 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........167547c818d6516454e0884b574300d3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15222667 09317597 |
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