Programming Tachycardia Zones to Reduce Avoidable Defibrillator Shocks
| العنوان: | Programming Tachycardia Zones to Reduce Avoidable Defibrillator Shocks |
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| المؤلفون: | Rita Marinheiro, Leonor Parreira, Cláudia Lopes, Pedro Amador, Dinis Mesquita, José Farinha, Ana Esteves, Joana Ferreira, Rui Coelho, Jeni Quintal, Rui Caria |
| المصدر: | Medical Research Archives. 10 |
| بيانات النشر: | Knowledge Enterprise Journals, 2022. |
| سنة النشر: | 2022 |
| الوصف: | Introduction: Most of avoidable defibrillator therapies can be reduced by evidence-based programming, but defining tachycardia configurations across all device manufacturers is not straightforward. Aims: To determine if a uniform programming of tachycardia zones, independently of the manufacturer, result in a lower rate of avoidable shocks in primary-prevention heart failure (HF) patients and also if programming high-rate or delayed therapies can have some benefit. Methods: Prospective cohort with historical controls. HF patients with a primary-prevention indication for a defibrillator were randomized to receive one of two new programming configurations (high-rate or delayed therapies). A historical cohort of patients with conventional programming was analyzed for comparison. The primary endpoint was any therapy [shock or anti-tachycardia pacing (ATP)] delivered. Secondary endpoints were appropriate shocks, appropriate ATP, appropriate therapies, inappropriate shocks, syncope and death. Results: 89 patients were assigned for new programming group [high rate (n=47) or delayed therapy (n=42)]. They were compared with 94 historical patients with conventional programming. During a mean follow-up of 20±7 months, the new programming was associated with a reduction in any therapy (HR = 0.265, 95% CI 0.121-0.577, p=0.001), even after adjustment. Aproppriate ATP and any shock were also reduced. Syncope did not occur. Sudden, cardiovascular and all-cause deaths were not different between the groups. In the new programming group, neither highrate nor delayed programming were better than the other. Conclusions: In our study, programming tachycardia zones homogeneously across all manufacturers was possible and resulted in a lower rate of therapies, shocks and appropriate ATP. |
| تدمد: | 2375-1924 2375-1916 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::17f8ef608b113ea2fd549fd462ebde36 https://doi.org/10.18103/mra.v10i7.2860 |
| رقم الأكسشن: | edsair.doi...........17f8ef608b113ea2fd549fd462ebde36 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23751924 23751916 |
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