Emerging antibiotic resistance pattern of urinary tract infection (UTI) due to Escherichia Coli (E.Coli)
| العنوان: | Emerging antibiotic resistance pattern of urinary tract infection (UTI) due to Escherichia Coli (E.Coli) |
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| المؤلفون: | null Salman Azhar, null Talha Munir, null Mian Sajjad Ahmed, null Wasif Baig, null Ahmed Nawaz Baber, null Khalid Pervez, null Ahsan Jahangir |
| المصدر: | The Professional Medical Journal. 28:1804-1811 |
| بيانات النشر: | Independent Medical Trust, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | biochemical phenomena, metabolism, and nutrition, bacterial infections and mycoses |
| الوصف: | Objective: To determine the emerging antibiotic resistance pattern of adult patients of MDR UTI cases caused by E.Coli. Study Design: Retrospective Data. Setting: Departments of Medicine and Obstetrics & Gynecology, Madinah Teaching Hospital / University Medical and Dental College, Faisalabad. Period: August 2016 to Sep 2018. Material & Methods: This retrospective study included 187 patients meeting the operational definition of multi-drug resistance cases of urinary tract infection caused by E. coli. All cases either male or female of age above 15 years with positive reports of urine culture and sensitivity for E.coli were included in the study. Along with the demographic variables urine WBC’s, results of urine culture and sensitivity were noted. Antibiotic sensitivity pattern of all the E.coli resistant UTI cases was analyzed. After identification of the microbe, antimicrobial sensitivity was accessed using Kirby–Bauer disc diffusion method on the Mueller–Hinton agar. The antimicrobial susceptibility test was performed against E. coli strains by using the following antibiotics: Piperacilin, Amoxicilin-Calvulanic, Pipmedic Acid, Cefipime, Ceftrixone, Cefuroxime, Cefoperazone-sulbactam, Ceftazidime, Cephradine, Ciprofloxacin, Ofloxacin, Levofloxacin, ofloxacin, Nitrofurantoin, Amikacin, Tombramycin, Gentamicin, Linezolid, Doxycycline, Sulphamethoxazole, Imipenem, Meropenem, Aztreonam in order to obtain an antibiogram. Results: In our data, 66.8% (n=125) were MDR UTI, and more than half of these cases were 63.2% (n=79) were females. Among the total 187 cases, 97.3% patients were resistant to most of the beta-lactam antibiotics, 95.7% were resistant to most of the quinolones and 68.4% were resistant to most of the aminoglycosides. Conclusion: This increasing antibiotic resistance is very alarming and steps should be taken to reduce the misuse of antibiotics. Studies should be done to control the risk factors leading to E. coli UTI. By following proper pharmacological guidelines, principles to use antibiotics and manage outpatient cases of UTIs, the incidence of MDR UTI can be controlled. |
| تدمد: | 2071-7733 1024-8919 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::19e3cd6b7c034ffe285a7076077b9e9e https://doi.org/10.29309/tpmj/2021.28.12.6364 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........19e3cd6b7c034ffe285a7076077b9e9e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20717733 10248919 |
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