11C-Methionine and 18F-2-Fluorodeoxy-glucose Positron Emission Tomography: A Tool for Diagnosis of Cerebral Glioma and Monitoring after Brachytherapy with 125l Seeds
| العنوان: | 11C-Methionine and 18F-2-Fluorodeoxy-glucose Positron Emission Tomography: A Tool for Diagnosis of Cerebral Glioma and Monitoring after Brachytherapy with 125l Seeds |
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| المؤلفون: | Harald Treuer, Juergen Voges, Volker Sturm, W. D. Heiss, Bernd Bauer, M. Würker, Rolf Schröder, T. Hölzer, Uwe Pietrzyk, Karl Herholz |
| المصدر: | Stereotactic and Functional Neurosurgery. 69:129-135 |
| بيانات النشر: | S. Karger AG, 1997. |
| سنة النشر: | 1997 |
| مصطلحات موضوعية: | medicine.medical_specialty, Methionine, medicine.diagnostic_test, business.industry, medicine.medical_treatment, Brachytherapy, Therapeutic effect, 11c methionine, Seed Implantation, medicine.disease, chemistry.chemical_compound, chemistry, Positron emission tomography, Glioma, medicine, Surgery, Neurology (clinical), Radiology, business, Nuclear medicine, Radiation treatment planning |
| الوصف: | Forty-six patients with suspected brain tumors were investigated by positron emission tomography (PET). Using 11C-methionine PET, the spatial extent of increased uptake in gliomas was larger than that of contrast enhancement on CT/ MR images in 67% or the same in 33%. Ten of 46 patients treated with brachytherapy for low-grade gliomas were also investigated with 18F-2-fIuorodeoxyglucose (FDG)-PET. One year after seed implantation, the glucose metabolism had not changed, but the decline of methionine uptake was significant. In conclusion, 11C-methionine PET may improve tumor delineation and, following brachytherapy, provides more information on the therapeutic effects than FDG. |
| تدمد: | 1423-0372 1011-6125 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::1bb29e26aa8f129989dfc0a8412dae28 https://doi.org/10.1159/000099864 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........1bb29e26aa8f129989dfc0a8412dae28 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14230372 10116125 |
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