Scarring Folliculitis in the Ectrodactyly-Ectodermal Dysplasia-Clefting Syndrome
| العنوان: | Scarring Folliculitis in the Ectrodactyly-Ectodermal Dysplasia-Clefting Syndrome |
|---|---|
| المؤلفون: | Max A. Spycher, J. Müller, Ralph M. Trüeb, Günter Burg, D. Tsambaos |
| المصدر: | Dermatology. 194:191-194 |
| بيانات النشر: | S. Karger AG, 1997. |
| سنة النشر: | 1997 |
| مصطلحات موضوعية: | chemistry.chemical_classification, Pili torti, medicine.medical_specialty, Ectodermal dysplasia, Ectrodactyly, integumentary system, business.industry, Folliculitis, Dermatology, Scarring alopecia, medicine.disease, Bone canaliculus, medicine.anatomical_structure, chemistry, Scalp, Keratin, medicine, medicine.symptom, business |
| الوصف: | Several clinical syndromes are characterized by ectodermal dysplasia (ED) in association with clefting of the lip and/or palate. In these syndromes, alopecia is primarily due to abnormalities of the hair shaft associated with increased hair fragility. Scalp dermatitis is yet another peculiar finding, primarily seen in the ankyloblepharon-ED-clefting (AEC) syndrome. We report on a 16-year-old patient with ectrodactyly-ED-clefting (EEC) syndrome, who exhibited a scarring alopecia due to deep folliculitis. On scanning electron microscopy, irregular torsion and longitudinal grooving of the hair shaft (pili torti et canaliculi) were observed. Quantitative determinations of the elastic and viscous parameters of hair demonstrated a normal viscosity but a significantly reduced hair elasticity, indicating either an abnormal composition or a disordered arrangement of microfibrils within the apparently normal keratin matrix. In contrast to the erosive scalp dermatitis of early onset in the AEC syndrome, alopecia in this case of EEC syndrome demonstrated follicular scarring with onset during puberty. We question a possible role of the anatomical hair abnormality in the pathogenesis of chronic deep folliculitis in this and clinically related syndromes. |
| تدمد: | 1421-9832 1018-8665 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::1db7978710ff2d8d69897b8ad715be5e https://doi.org/10.1159/000246097 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........1db7978710ff2d8d69897b8ad715be5e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14219832 10188665 |
|---|