Studies in Meconium: Disaccharidase Activities in Meconium From Cystic Fibrosis Patients and Controls
| العنوان: | Studies in Meconium: Disaccharidase Activities in Meconium From Cystic Fibrosis Patients and Controls |
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| المؤلفون: | I. Antonowicz, S. Ishida, H. Shwachman |
| المصدر: | Pediatrics. 56:782-787 |
| بيانات النشر: | American Academy of Pediatrics (AAP), 1975. |
| سنة النشر: | 1975 |
| مصطلحات موضوعية: | congenital, hereditary, and neonatal diseases and abnormalities, fluids and secretions, embryonic structures, Pediatrics, Perinatology and Child Health |
| الوصف: | Meconium ileus represents the earliest clinical manifestation of cystic fibrosis. The differences found in the composition and amount of protein, mucoprotein, mucopolysaccharides, and reducing sugars in meconium from newborns with cystic fibrosis might be of significance relative to the pathogenesis and early diagnosis of this disease. We studied the enzymatic activity of disaccharidases (lactase, sucrase, maltase, and palatinase) in meconium of infants with cystic fibrosis and controls. We found an increase in the specific activity of these enzymes in the meconium from infants with cystic fibrosis as compared to the specific activity in meconium from normal infants. The increase in the activities, expressed as micromols per gram of protein per minute was: lactase, 100 times higher; sucrase, 18 times; maltase, 4.8 times; and palatinase, 8.9 times. |
| تدمد: | 1098-4275 0031-4005 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::1ecdd136bfa079a4dc5eb9af2b4547cc https://doi.org/10.1542/peds.56.5.782 |
| رقم الأكسشن: | edsair.doi...........1ecdd136bfa079a4dc5eb9af2b4547cc |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10984275 00314005 |
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