P1672Late right heart failure predictors after left ventricular assist device implantation
| العنوان: | P1672Late right heart failure predictors after left ventricular assist device implantation |
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| المؤلفون: | N Bouzas Cruz, O Gonzalez Fernandez, Guy A. MacGowan, C. Ferrera Duran, S. Tovey, S. Schueler, A. Woods, N. Robinson-Smith |
| المصدر: | European Heart Journal. 40 |
| بيانات النشر: | Oxford University Press (OUP), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | medicine.medical_specialty, Right heart failure, Tricuspid Valve Insufficiency, business.industry, Ventricular assist device, medicine.medical_treatment, Internal medicine, medicine, Cardiology, Cardiology and Cardiovascular Medicine, business |
| الوصف: | Background Right heart failure (RHF) after left ventricular assist device (LVAD) implantation is a significant cause of morbidity and mortality. While multiple predictors of early RHF have been described, information on late RHF is scarce. The aim of this study was to identify predictors of late RHF in LVAD patients. Methods A retrospective analysis of all adult patients who underwent HeartWare-VAD implantation for ischemic heart disease or non-ischemic dilated cardiomyopathy in a single centre was performed. Late RHF was defined as RHF requiring hospitalization and medical treatment after 30 days of LVAD implantation. Results A total of 16 (10.3%) patients from 156 implantations developed late RHF. Patients developing late RHF were older at time of surgery, 56.7±6.9 vs 49.5±12.5 years; p Multivariate Cox proportional-hazards analysis for late right heart failure Variable Hazard ratio 95% confidence interval P-value Tricuspid regurgitation- moderate or severe 5.50 1.34–22.58 0.02 Mitral regurgitation (discharge)- moderate or severe 3.54 1.14–11.02 0.03 Age 1.07 1.01–1.14 0.03 Right ventricular basal diameter 1.14 0.43–3.03 0.79 Right ventricular fractional area change 0.98 0.87–1.10 0.79 Multivariate analysis showing predictors of late right heart failure according to a multivariate model. Late RHF according to TR severity Conclusions Pre-operative significant tricuspid regurgitation and mitral regurgitation after implantation predict the occurrence of late RHF. Prospective studies are needed to determine whether tricuspid valve interventions may reduce late RHF. |
| تدمد: | 1522-9645 0195-668X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::23033478bc1cdb2237d1e3a735242270 https://doi.org/10.1093/eurheartj/ehz748.0429 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........23033478bc1cdb2237d1e3a735242270 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15229645 0195668X |
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