التفاصيل البيبلوغرافية
العنوان: [Untitled]
المؤلفون: Erika Volckova, Rathindra N. Bose, Lea P. Dudones
المصدر: Pharmaceutical Research. 19:124-131
بيانات النشر: Springer Science and Business Media LLC, 2002.
سنة النشر: 2002
مصطلحات موضوعية: Pharmacology, Cisplatin, chemistry.chemical_classification, Chemistry, Organic Chemistry, Pharmaceutical Science, chemistry.chemical_element, Glutathione, In vitro, chemistry.chemical_compound, Mechanism of action, Biochemistry, medicine, Thiol, Molecular Medicine, Pharmacology (medical), medicine.symptom, Platinum, DNA, Biotechnology, medicine.drug, Cysteine
الوصف: Purpose. The purpose of this work is to evaluate the extent of the binding of cisplatin (cis-diamminedichloroplatinum(II)) to DNA in the presence and absence of biological thiols, glutathione, and cysteine, and to test the hypothesis whether the platinum-thiol complexes can serve as a drug reservoir for subsequent binding to DNA.
تدمد: 0724-8741
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2527c4bd37bbc273376da06b4f3fda5f
https://doi.org/10.1023/a:1014268729658
رقم الأكسشن: edsair.doi...........2527c4bd37bbc273376da06b4f3fda5f
قاعدة البيانات: OpenAIRE