General and user-friendly protocol for the synthesis of functionalized aryl- and heteroaryl-cyclopropanes by Negishi cross-coupling reactions

التفاصيل البيبلوغرافية
العنوان: General and user-friendly protocol for the synthesis of functionalized aryl- and heteroaryl-cyclopropanes by Negishi cross-coupling reactions
المؤلفون: Brian M. Coleridge, Andreas Leitner, Charles S. Bello
المصدر: Tetrahedron Letters. 50:4475-4477
بيانات النشر: Elsevier BV, 2009.
سنة النشر: 2009
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Negishi coupling, Bromide, Aryl, Organic Chemistry, Drug Discovery, Halide, Organic chemistry, Moiety, Biochemistry, Coupling reaction
الوصف: The introduction of an unsubstituted cyclopropyl moiety was efficiently accomplished via Negishi cross-coupling of cyclopropylzinc bromide with functionalized aryl halides in high yields and fast reaction rates. The stability and the efficient one-step synthesis of cyclopropylzinc bromide make this protocol very valuable in particular for commercial applications.
تدمد: 0040-4039
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::275b7d2044cd04b1f2007dff342d20a2
https://doi.org/10.1016/j.tetlet.2009.05.054
حقوق: CLOSED
رقم الأكسشن: edsair.doi...........275b7d2044cd04b1f2007dff342d20a2
قاعدة البيانات: OpenAIRE