Prospective, longitudinal study of risk factors for cancer-related distress in colorectal cancer survivors from prior to surgery until one year after surgery: Results from the ColoCare study
| العنوان: | Prospective, longitudinal study of risk factors for cancer-related distress in colorectal cancer survivors from prior to surgery until one year after surgery: Results from the ColoCare study |
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| المؤلفون: | Adetunji T. Toriola, Claire J. Han, Jennifer Ose, Cornelia M. Ulrich, Erin M. Siegel, Paul B. Jacobsen, Christopher I. Li, Anita R. Peoples, David Shibata, William M. Grady, Torsten Koelsch, Yakup Kulu, Martin F. Schneider, Graham A. Colditz, Karen L. Syrjala, Biljana Gigic, Alexis Ulrich, Jane C. Figueiredo |
| المصدر: | Journal of Clinical Oncology. 37:146-146 |
| بيانات النشر: | American Society of Clinical Oncology (ASCO), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Cancer Research, medicine.medical_specialty, Longitudinal study, Distress, Oncology, Colorectal cancer, business.industry, Internal medicine, Cancer related distress, medicine, medicine.disease, business |
| الوصف: | 146 Background: Although cancer-related distress is known to persist long after completion of colorectal cancer (CRC) treatment, factors related to distress are largely unexplored in CRC survivors. We examined changes over time and risk factors for distress in CRC patients over the first year after surgery. Methods: We included 212 CRC patients who consented pre-surgery, with data at 6 and 12 months post-surgery from the ColoCare Study in Heidelberg, Germany. Sociodemographic and lifestyle factors, social support and health-related quality of life (QOL) prior to surgery were evaluated as predictors of cancer-related distress. Distress was measured with the Cancer and Treatment Distress instrument (CTXD). Linear regression analyses examined associations between risk factors and distress. Results: Although overall mean of six distress subscales did not change from 6 to 12 months, distress subscale scores varied over time: health burden subscale score increased ( p < .001), while finances ( p = .004), medical demands ( p < .001), and identity ( p < .001) subscale scores decreased from 6 to 12 months. Uncertainty and family strain subscale scores did not change. Younger age, lower income, advanced cancer stage, poorer social support, and poorer baseline QOL scores predicted worse distress at 6 and 12 months. Conclusions: Cancer-related distress continues unresolved at 6 and 12 months post-surgery in this population of CRC survivors. Although some risk factors are difficult to alter, lack of social support may be modifiable and those at risk can be identified early after diagnosis. Screening for risk factors pre-surgery would allow for targeted interventions including strategies to improve resources for those with low support, thereby reducing long-term distress in CRC survivors. |
| تدمد: | 1527-7755 0732-183X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::2a1c6e5a735ce1aa647add1644eef42a https://doi.org/10.1200/jco.2019.37.31_suppl.146 |
| رقم الأكسشن: | edsair.doi...........2a1c6e5a735ce1aa647add1644eef42a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15277755 0732183X |
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