Objective The aim of this study was to evaluate the effect of size and location on removal rate using sialendoscopy alone for the management of sialolithiasis in the submandibular and parotid glands. Methods The Wharton’s duct and the Stensen’s duct were divided into 2 and 3 parts, respectively. All calculi were also examined preoperatively for their size and location in computed tomography images. Patients at our hospital with sialolithiasis who were treated with sialendoscopy alone were analyzed retrospectively to investigate whether the size and location of calculi correlated with removal rate. Results The removal rate of ductal calculi was significantly higher than of hilar calculi in the submandibular gland. A correlation between size and removal rate was observed in Wharton’s ductal calculi. In parotid sialolithiasis, no correlation was seen between removal rate and the size or location of calculi. Conclusion We concluded that sialendoscopy treatment alone is safe and resulted in favorable outcomes. However, the removal rate varies depending on the location.