Penicillin biosynthesis: conversion of deuteriated (L-α-amino-δ-adipyl)-L-cysteinyl-D-valine into isopenicillin N by a cell-free extract of Cephalosporium acremonium
التفاصيل البيبلوغرافية
العنوان:
Penicillin biosynthesis: conversion of deuteriated (L-α-amino-δ-adipyl)-L-cysteinyl-D-valine into isopenicillin N by a cell-free extract of Cephalosporium acremonium
The tripeptide (L-α-amino-δ-adipyl)-L-cysteinyl-D-[22H, Me2–2H6]valine was converted into isopenicillin N by a cell-free extract ofCephalosporium acremonium;; complete retention of all deutrons was confirmed by 2H n.m.r. spectroscopy
