Treatment planning for non-small cell lung tumours: VMAT versus 3DCRT a quantitative dosimetric study
العنوان: | Treatment planning for non-small cell lung tumours: VMAT versus 3DCRT a quantitative dosimetric study |
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المؤلفون: | Brian Dubos, M. Rogé, Yann Lauzin, Ahmed Hadj Henni, David Gensanne, Nicolas Pirault, Sébastien Thureau, Perrine Clarisse |
المصدر: | Journal of Radiotherapy in Practice. 19:327-332 |
بيانات النشر: | Cambridge University Press (CUP), 2019. |
سنة النشر: | 2019 |
مصطلحات موضوعية: | medicine.medical_specialty, business.industry, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, Medicine, Radiology, Nuclear Medicine and imaging, Radiology, Non small cell, Lung tumours, business, Radiation treatment planning |
الوصف: | Purpose:The dosimetric impact of volumetric modulated arc therapy (VMAT) in lung cancer compared with 3D conformal radiotherapy (3DCRT) is well known. However, this improvement is often associated with an increase in low doses. The aim of this study is to quantify these results more accurately.Methods:For each patient treated with 3DCRT, a second VMAT treatment plan was calculated. Usual dosimetric parameters such as target coverage or dose to the organs at risk were used to achieve the comparisons.Results:For planning target volume, homogeneity and conformity indices showed superiority of VMAT (respectively 0·07 and 0·87) compared to 3DCRT (0·11 and 0·57). For spinal cord planning organ at risk volume, the median maximum dose was 45·6 Gy in 3DCRT against 19·3 Gy in VMAT. Heart volume receiving at least 35 Gy (V35) decreased from 15·64% in 3DCRT to 8·28% in VMAT. Oesophagus V50 was higher in 3DCRT (25·45%) than in VMAT (14·03%). The mean lung dose was 17·9 Gy in 3DCRT versus 15·5 Gy in VMAT. Moreover, volumes receiving 5, 10 and 15 Gy were not significantly different between the two techniques when VMAT was performed with partial arcs.Conclusion:All the dosimetric parameters were improved with VMAT compared to the 3DCRT without increasing low doses when using partial arcs. |
تدمد: | 1467-1131 1460-3969 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::2dcc0df2a673fab1195489d1d479143c https://doi.org/10.1017/s1460396919000864 |
حقوق: | CLOSED |
رقم الأكسشن: | edsair.doi...........2dcc0df2a673fab1195489d1d479143c |
قاعدة البيانات: | OpenAIRE |
تدمد: | 14671131 14603969 |
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