Katz frailty syndrom has no predictive value in low-risk patients undergoing transcatheter aortic valve implantation
| العنوان: | Katz frailty syndrom has no predictive value in low-risk patients undergoing transcatheter aortic valve implantation |
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| المؤلفون: | K Byczkowska, A Pawlak, R J Gil |
| المصدر: | European Heart Journal. 42 |
| بيانات النشر: | Oxford University Press (OUP), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Cardiology and Cardiovascular Medicine |
| الوصف: | Background Aortic stenosis is a disease of the elderly people, with multiple comorbidities and often with the frailty syndrome. Therefore, we decided that frailty as a clinical factor requires precise characterization in low-, intermediate– and high-risk patients as it may be a valuable supplement to the risk stratification in TAVI. Purpose The aim of our study was to evaluate the prognostic value of the Katz frailty scale in patients undergoing TAVI in relation to the risk of mortality assessed with the STS scale. Methods The study included 105 patients (mean age 82.36±4.5) with severe AS treated with TAVI at the Department of Cardiology of our clinical hospital. Each patient had laboratory tests, ECG, echocardiography and was assessed based on the STS scale and the Katz frailty scale. Study population was divided into groups: I with moderate and severe Katz frailty syndrome (≤4 pts) and II with mild Katz frailty syndrome (≥5 pts). Follow-up observations were carried out at 1 month and 1 year. Results In the study population 46% were men, the mean age was 82.36±4.5 years, the mean STS score was 7.03±4.24%, and the Katz frailty syndrome with the degree of ≤4 pts was found in 44,8%. There was a statistically significant reduction in Katz frailty score at 1 month and 1 year (n=40, 40%; n=21, 26%; p≤0,05, p≤0,05 respectively) compared to before TAVI. The greatest improvement was observed in the intermediate- and high-risk patients in 1-year follow up (p≤0,05, p≤0,05 respectively) (Tab.1). There was no significant change (p>0.05) between 1-month and 1-year follow-up. 1-year all-causes mortality in patients with moderate and severe Katz frailty syndrome was 30% and with mild Katz frailty syndrome was 3% (p Conclusion A significant correlation was demonstrated between survival and Katz frailty score. The Katz frailty score had a significant prognostic value, especially in intermediate- and high risk patients, but no in low-risk patients. Katz frailty score and STS risk score significantly correlated with the risk of death from cardiovascular causes in patients undergoing TAVI. Funding Acknowledgement Type of funding sources: None. Figure 1Table 1 |
| تدمد: | 1522-9645 0195-668X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::2f5152c5deaff0c4d458dbcabb7b07ff https://doi.org/10.1093/eurheartj/ehab724.1633 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........2f5152c5deaff0c4d458dbcabb7b07ff |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15229645 0195668X |
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