The lateral-torsional buckling behavior of I-beams with web openings has been a topic of interest among structural engineers for many years. The presence of a web opening in the beam can significantly affect its strength and stiffness, making it more prone to buckling failure. Therefore, understanding the buckling behavior of I-beams with web openings is crucial for the design of steel structures. Finite Element Analysis (FEA) has become a widely used tool for investigating the behavior of structures under different loading conditions. In this study, FEA was used to analyze the lateral-torsional buckling behavior of I-beams with web openings. The software used for the analysis was ETABS, which is a widely used software for analyzing and designing buildings and other structures. The objective of the study was to investigate the effects of different web opening shapes, sizes, and locations on the buckling strength of the beam. The FEA simulations were validated using experimental data available in the literature. The study analyzed different types of web openings, such as circular, rectangular, and elliptical shapes, and various sizes and locations of the web opening along the beam span. The results of the study showed that the presence of a web opening significantly reduced the strength and stiffness of the I-beam, making it more susceptible to buckling failure. The location of the web opening had a more significant effect on the buckling behavior than its size and shape. The results of the FEA simulations were found to be in good agreement with the experimental data available in the literature, which validates the accuracy of the ETABS software in predicting the buckling behavior of I-beams with web openings