58 Clinical manifestations and disease severity of SARS-CoV-2 infection among infants in Canada
| العنوان: | 58 Clinical manifestations and disease severity of SARS-CoV-2 infection among infants in Canada |
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| المؤلفون: | Pierre-Philippe Piché-Renaud, Luc Panetta, Daniel Farrar, Charlotte Moore Hepburn, Olivier Drouin, Jesse Papenburg, Marina Salvadori, Melanie Laffin-Thibodeau, Fatima Kakkar, Shaun Morris |
| المصدر: | Paediatrics & Child Health. 27:e28-e28 |
| بيانات النشر: | Oxford University Press (OUP), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Pediatrics, Perinatology and Child Health |
| الوصف: | Background There are limited data on outcomes of SARS-CoV-2 infection among infants ( Objectives The objective of this study was to describe the clinical manifestations, disease severity, and characteristics associated with hospitalization among infants infected with the initial strains of SARS-CoV-2. Design/Methods This is a nationwide prospective observational study using the infrastructure of the Canadian Paediatric Surveillance Program. All cases of infants aged Results A total of 531 cases were reported, including 332 (62.5%) non-hospitalized and 199 (37.5%) hospitalized infants. Among hospitalized infants, 141 of 199 infants (70.9%) were admitted because of COVID-19-related illness, and 58 (29.1%) were admitted for reasons other than acute COVID-19. Amongst all cases with SARS-CoV-2 infection, the most common presenting symptoms included fever (66.5%), coryza (47.1%), cough (37.3%) and decreased oral intake (25.0%). In our main analysis, infants with a comorbid condition had higher odds of hospitalization compared to infants with no comorbid conditions, and infants Conclusion We describe one of the largest cohorts of infants with SARS-CoV-2 infection. Overall, severe COVID-19 in this age group is uncommon with most infants having mild disease. Comorbid conditions and younger age were associated with COVID-19-related hospitalization amongst infants. |
| تدمد: | 1918-1485 1205-7088 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::3717c7dcf2de0f0145e011b4c5a3a562 https://doi.org/10.1093/pch/pxac100.057 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........3717c7dcf2de0f0145e011b4c5a3a562 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19181485 12057088 |
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