The soil inhabits many microbes, including plant parasitic nematodes. Plant parasitic nematodes are reported to cause substantial damage to crops which results in yield and economic losses. Chemical control is the most widely used method to control plant parasitic nematodes. However, the consequences of synthetic chemicals are detrimental to human health, animals, and the environment and face so many strict regulatory measures. Synthetic chemicals are also not reliable with their inability to provide long-term protection. Many studies have shown that the use of beneficial fungi and bacteria has the potential to prevent and suppress plant parasitic nematodes while keeping the environment safe. Several experiments have demonstrated that bioproducts of microbial origin are cheap, safe, and provide long-lasting biocontrol effects against pathogens both in vitro and field conditions. Therefore, this review aims to discuss mechanisms that beneficial microbes and their products use to successfully suppress plant parasitic nematodes. The review also explains the importance of using commercial bionematicides in the sustainable management of plant parasitic nematodes. The existing challenges that are limiting the full application of beneficial microbes, and what needs to be done to fully utilize biocontrol agents in the management of plant parasitic nematodes have also been discussed. To the best of our knowledge, this review has come at the right time to give researchers and plant growers more options when several synthetic chemical nematicides are being banned by regulatory authorities due to their hazardous effects.
