Randomized controlled trials published on patients with hernias have a high percentage of unreproducible statistics
| العنوان: | Randomized controlled trials published on patients with hernias have a high percentage of unreproducible statistics |
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| المؤلفون: | Oscar A. Olavarria, Mike K. Liang, Julie L. Holihan, Cynthia S. Bell, Naila H Dhanani |
| المصدر: | Hernia. 26:745-749 |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Number generator, business.industry, medicine.disease, law.invention, Exact test, Search terms, Randomized controlled trial, law, Statistical significance, Statistics, Medicine, Surgery, Hernia, p-value, business, Statistical hypothesis testing |
| الوصف: | Surgeons rely on randomized controlled trials (RCT) to compare the effectiveness of treatments. RCTs require careful planning and substantial effort to complete. Because of the careful study design, statistics performed are often easy to reproduce such as Chi-squared or t-test. Issues such as statistical discordance, or reporting statistical results that cannot be reproduced, should be uncommon. RCTs pertaining to hernias were identified in PubMed using the search terms “hernia” and “randomized controlled trial.” Studies were selected using a random number generator. Studies were included if the primary outcome could be reproduced using the data and statistical test reported in the manuscript. Discordance between the obtained p-value from our analysis and the published p-value was assessed. Primary outcome was the number of studies that reported p-values that crossed the level of statistical significance (p-value = 0.05) but on reproduction analysis did not. Of the 100 included RCTs, five reported p-values that crossed the “p = 0.05” threshold that our team was unable to reproduce using the statistical test reported in the manuscript. An additional three studies reported p-values that crossed the “p = 0.05” threshold that our team was unable to reproduce using the appropriate statistical test (i.e., Fisher’s exact test when all expected cell counts |
| تدمد: | 1248-9204 1265-4906 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::3a6dcc00d88119abf7e6b305f0d4c85a https://doi.org/10.1007/s10029-021-02488-4 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........3a6dcc00d88119abf7e6b305f0d4c85a |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 12489204 12654906 |
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