Ginseng plants associated with a number of fungi, several of which are reported to protect it from pathogens, thus improving plant growth. This study aimed to screen Panax ginseng leaves for endophytic fungi and to assess these fungi for their efficacy to inhibit ginseng black spot disease caused by Alternaria panax. A total of 256 endophytic fungal isolates were obtained from P. ginseng leaves. Most of the fungal isolates belonged to Chaetomium, Nemania, Xylaria, Nodulisporium and Alternaria; the others were not identified. One isolate Chaetomium globosum (FS-01), inhibited on A. panax causes black spot disease of ginseng, suggesting that FS-01 can be a potential biocontrol resource for control of ginseng black spot diseases. This is the first report on C. globosum, an endophytic fungus as biocontrol agent for ginseng black spot. Key words: Panax ginseng, inhibitory effect, Chaetomium globosum, biological control.
