Studies on the lethal effects of plants on harmful microorganisms have made them an important and valuable resource for health. Turkey, wherefore the junction center of three phytogeographic regions, is home to numerous medicinal and aromatic plants with its rich flora. L. canescens is a perennial plant that grows in a geography extending from Turkey to Iran, and there are studies on the plant only on its antioxidant capacity and essential oil content. In this study, antimicrobial activity of hexane, ethylacetate, methanol and water extracts of aerial parts of L. canescens, which has known as “Topajdarbaşı” in Turkey, was investigated. Plant samples were collected from Pöske Mount in Erzincan. Antimicrobial activities of extracts were evaluated using disc diffusion method against Gram-negative bacterias (Pseudomonas aeruginosa, Klebsiella pneumoniae, colistin-resistant Escherichia coli, Escherichia coli) and Gram-positive bacterias (Enterococcus faecalis, Staphylococcus aureus, Streptococcus pneumoniae). To conclude, hexane, ethylacetate and methanol extracts of L. canescens showed considerable antimicrobial activity against S.aureus, E.faecalis, S.pneumoniae strains.
