BACTERIAL AND VIRAL COPROANTIBODIES IN BREAST-FED INFANTS
| العنوان: | BACTERIAL AND VIRAL COPROANTIBODIES IN BREAST-FED INFANTS |
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| المؤلفون: | Jean F. Kenny, Mary I. Boesman, Richard H. Michaels |
| المصدر: | Pediatrics. 39:202-213 |
| بيانات النشر: | American Academy of Pediatrics (AAP), 1967. |
| سنة النشر: | 1967 |
| مصطلحات موضوعية: | fluids and secretions, Pediatrics, Perinatology and Child Health |
| الوصف: | Stools of newborn breast-fed infants may contain significant amounts of hemagglutinating antibody to enteropathogenic E. coli and neutralizing antibody to polioviruses. Stool titers averaged only fourfold lower than maternal milk titers for antibacterial and less than twofold lower for antiviral activity. Similar ratios of stool:milk activity were also found for paired specimens obtained during the second and third postpartum months. The stool antibodies were stable at 56°C and exhibited definite specificity. Bacterial hemagglutinins in feces were more sensitive to mercaptoethanol than the poliovirus neutralizing activity. Stools from breast-fed infants contained gamma-1 globulins similar to those in milk, including IgA and small amounts of IgM. Meconium from bottle-fed infants with high serum antibody titers to polioviruses contained traces of homotypic neutralizing antibody. Antiviral and antibacterial activity were not detected in transitional and later stools from artificially fed infants, nor were human immune globulins. Milk bacterial hemagglutinating antibodies were more resistant to acid and to pepsin than those in serum. Furthermore, acid had a less deleterious effect on virus neutralizing activity in milk than it had on that in serum, and it also had less effect on the milk antiviral than on the milk antibacterial antibodies. |
| تدمد: | 1098-4275 0031-4005 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::400820d3cd135e4a4133ec69eb9b9a14 https://doi.org/10.1542/peds.39.2.202 |
| رقم الأكسشن: | edsair.doi...........400820d3cd135e4a4133ec69eb9b9a14 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10984275 00314005 |
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