Bacterial diseases in fishes create one of the alarming situations that render significant loss to the fishing industries and aquacultural farm units worldwide. Various drugs have been formulated, standardized, and used in the industry to combat bacterial infections. However, non-judicious drugs can lead to pharmacological problems and induction of toxicity in fishes, leaving them less suitable for human consumption. These drugs can be supplemented with the natural herb plants having antibacterial activities, although they cannot be used solely to curb the menace. Therefore, the review put forth an idea, which plant herbs can be used as antibacterial drugs in fishes.